03-11-08 Lazio 2-0 Copenhaghe (Kalou, Joe Cole)
07-11-08 Nuremberg 0-3 Lazio (ali no presentada)
10-11-08 Lazio 5-0 Olympique Lyonnais (Joe Cole 3, Scaloni, Kalou)
13-11-08 Celtic de Glasgow 0-3 Lazio (ali no presentada)
17-11-08 Lazio 2-1 San Lorenzo (Kalou, Cribari)
24-11-08 AEK Atenas 2-4 Lazio (Ameobi, Rocchi 2, Kalou)
27-11-08 Lazio 1-0 Atletico de Madrid (Rocchi)
01-12-08 Boca Juniors 0-0 Lazio
04-12-08 Lazio 0-4 Benfica
15-12-08 Villarreal 0-1 Lazio (Scaloni)
18-12-08 Milan 1-0 Lazio
22-12-08 Lazio 3-1 Hertha Berlin (Kalou 2, Alex)
08-01-09 Stuttgart 4-3 Lazio (Ledesma, Scaloni, Rocchi)
12-01-09 Lazio 1-0 Girondins (Scaloni)
19-01-09 Olympiakos 1-1 Lazio (Sclaoni)
02-02-09 Aston Villa 0-3 Lazio (ali no presentada)
09-02-09 Lazio 7-5 Nuremberg (Mudingayi, Paulo Ferreira 2, Kalou 2, Alex, Joe Cole)
16-02.09 Olympique Lyonnais 0-3 Lazio (Kalou, Anderson PP; Scaloni)
23-02-09 Lazio 2-1 Celtic de Glasgow (Joe Cole, Kalou)
09-03-09 Vasco da Gama 0-2 Lazio (Kalou, Scaloni)
23-03-09 Lazio 3-1 AEK Atenas (Joe Cole, Kalou, Cahais)
26-03-09 Atletico de Madrid 2-0 Lazio
30-03-09 Lazio 1-0 Boca Juniors (Megnhi)
02-04-09 Benfica 2-0 Lazio

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